Software developed by the Heath-e-Child project is capable of comparing a variety of structured and unstructured data to help identify rare or life-threatening diseases in children and then model the potential progression of those diseases. The software can search and compare patient data from hospitals throughout Europe, allowing doctors to study how patients with similar data at other hospitals were treated and whether treatment was successful. The Health-e-Child system links anonymized databases of patient information from hospitals in Paris, Genoa, Rome, and London, and there are plans to extend the network to 25 hospitals. For unstructured data such as images, the project has developed tools that translate visual information into a machine-readable language. The project’s three-dimensional (3D) registration tool for magnetic resonance imaging (MRI) scans and its MRI erosion-scoring system for juvenile idiomatic arthritis have been recognized as major advances. The project’s CaseReasoner tool enables doctors to search thousands of disease diagnoses, treatments, and outcomes to find similar cases. And the CardioWiz tool can be combined with MRI scan measurements to rapidly generate animated 3D models of a patient’s heart that can be used to simulate the effects of heart surgery or drug treatments.
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